Speakers

Keynote

The Versatile Macrophage: Receptors and Inflammation
Siamon Gordon, M.D., Ph.D.
Emeritus Professor of Cellular Pathology, University of Oxford
Visiting Scientist at the NIH

Symposium Titles & Co-Chairs

1. Tissue Crosstalk in Inflammation and Metabolism: Adipokines and Myokines
   
   Co-chairs: Steven Simpson, Ph.D. (GSK) & Ken Walsh, Ph.D., (Boston Univ)

   Speaker 1: Gokhan Hotamisligil, M.D., Ph.D. (Harvard)
   Reciprocity of Metabolism and Inflammation
   
   Speaker 2: Ken Walsh, Ph.D. (Boston Univ)
   Adipokines, Myokines and Metabolic Disease
   
   Speaker 3: Bente Pederson, M.D. (Univ of Copenhagen)
   Skeletal Muscle as an Endocrine Organ: The Rold of Myokines in Muscle-Fat Cross-Talk
   
   Speaker 4: Jennifer Lachey, Ph.D. (Acceleron Pharma)
   Treatment with a Soluble Activin Receptor Type IIB Attenuates Diet-Induced Obesity in High-Fat Diet-Fed Mice
    

2. ADVANCES in Translational Medicine as it Applies to Inflammatory Diseases

   Co-Chairs: Lisa Schopf, Ph.D. (Verdante Pharmaceuticals) & Bill Selig, Ph.D.
   
   Speaker 1: Jeff Voss, Ph.D. (Abbott)
   Translational Analysis of Autoimmune Disease mRNA Expression Data

   Speaker 2: Bitao Liang, Ph.D. (Celgene)
   Mesenchymal Stromal (MSC)-Like Cells in Autoimmune and Anti-Inflammatory Applications
   
   Speaker 3: Christine Ward, Ph.D. (MedImmune)
   Translational Strategies for Respiratory Drug Development
   
   Speaker 4: William Westlin, Ph.D. (Avila Therapeutics)
   Translational Pharmacology of AVL-292, A Potent and Selective Inhibitor of Bruton’s Tyrosine Kinase
    

3. Molecular and Cellular Crosstalk in Inflammation Network: the Role of Macrophages and Dendritic Cells
   
   Co-Chairs: Annalisa D'Andrea, Ph.D. (SRI Int Biosciences) & Liwu Li, Ph.D. (Virginia Tech)
   
   Speaker 1: Giorgio Trinchieri, M.D. (NCI)
   Innate Resistance, Inflammation and Cancer
   
   Speaker 2: Carla Rothlin, Ph.D. (Yale)
   TAMing Inflammation In Vivo
   
   Speaker 3: Kate Fitzgerald, Ph.D. (U Mass)
   Cytosolic DNA Sensors and Innate Immunity
   
   Speaker 4: Stefanie Vogel, Ph.D. (U Maryland)
   Role of Alternatively Activated Macrophages in the Resolution of RSV-Induced Disease
    
4. Lupus: From Basic Mechanisms to the Clinic
   
   Co-Chairs: Laura Carter, Ph.D. (Array BioPharma) & Joan Merrill, M.D. (Oklahoma Medical Res Found)
   
   Speaker 1: Gregg Silverman, M.D. (UCSD)
   Roles of B Cells in Lupus Pathogenesis
   
   Speaker 2: Franck Barrat, Ph.D. (Dynavax)
   Plasmacytoid Dendritic Cell Activation Hampers Glucocorticoids Anti-Inflammatory Activity in SLE
   
   Speaker 3: Joan Merrill, M.D. (Oklahoma Medical Res Found)
   Overview of Lupus Clinical Development Programs
    
5. Novel Therapeutics
   
   Co-Chairs: Bruce Tomczuk, Ph.D. (Arginetix) & Spencer Danto, M.D., Ph.D. (Pfizer)
   
   Speaker 1: Alison Humbles, Ph.D. (MedImmune)
   MEDI-563, A Humanized Anti-IL-5 Receptor Alpha MAb with Enhanced Antibody-Dependent Cell-Mediated Function for the Treatment of Asthma
   
   Speaker 2: Marina Roell, Ph.D. (XOMA)
   Regulating IL-1 Activity with XOMA 052, A Therapeutic Antibody with a Novel Mechansim of Action
   
   Speaker 3: David Martin, M.D. (Amgen)
   Targeting the IL-17 Axis: From Bench to Bedside

Mini Symposia

1. Innate Immune Responses
   Co-Chairs: Laurent Audoly, Ph.D. (Merck) & Bassil Dahiyat, Ph.D. (Xencor)
   Invited Speaker: Basil Dahiyat, Ph.D. (Xencor)
   Tuning Effector Cell Responses to MAb Therapies via Fc Engineering: Clinical and Pre-Clinical Experiences
   
   Plus 4 oral presentations selected from submitted abstracts
    
2. Adaptive Immune Responses
   Co-Chairs: Robert Benschop, Ph.D. (Lilly) & Barb Vilen, Ph.D. (UNC)
   Invited Speaker: Barb Vilen, Ph.D. (UNC)
   Regulating Immunoglobulin Secretion During Adaptive Immune Responses
   
   Plus 4 oral presentations selected from submitted abstracts

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